Thermo Fisher Scientific Plasminogen Polyclonal Antibody
Thermo Fisher Scientific의 Plasminogen Polyclonal Antibody는 인간 플라스미노겐을 인식하는 토끼 다클론 항체입니다. WB, IHC, Flow Cytometry에 적합하며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA514196
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 636–665 from the C-terminal region of human PLG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2252642 |
Target Information
Plasminogen is a plasma protein synthesized primarily in the liver. It consists of a single polypeptide chain with a molecular weight of approximately 88.5 kDa and a plasma concentration of 70–200 mg/L. Plasminogen is activated by tissue plasminogen activator, urokinase, or streptokinase to form plasmin. Activation involves cleavage and release of the preactivation peptide. Plasmin comprises a heavy (A) chain containing five kringle domains and a light (B) chain with the active site. It functions as a trypsin-like protease that degrades fibrin, playing a critical role in fibrinolysis. Defects in plasminogen can lead to reduced fibrinolytic activity and result in recurrent thrombosis, thrombophlebitis, or pulmonary embolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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