Thermo Fisher Scientific TRK fused gene Recombinant Rabbit Monoclonal Antibody (SD082-0)
TRK fused gene를 인식하는 Recombinant Rabbit Monoclonal Antibody로, Western blot, IHC, ICC/IF에 사용 가능. 높은 특이성과 재현성을 제공하며, Protein A 정제 및 동물유래 성분이 없는 포뮬레이션. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD082-0 |
| Immunogen | Synthetic peptide within Human TRK aa 351–400 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809655 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
TFG (TRK fused gene) is a human homolog of mouse TFG protein. It contains an N-terminal coiled-coil structure, a SPYGQ-rich region, and octicosapeptide repeats.
Research indicates:
- TFG modulates SHP-1 activity
- Acts as a novel member of the NF-κB pathway
- Associates with proteins such as TANK and NEMO
- Involved in oncogenic rearrangements with NTRK1 (thyroid TRK-T3 oncogene), ALK (anaplastic lymphoma), and NOR1 (myxoid chondrosarcoma)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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