Thermo Fisher Scientific RUNX1/RUNX2/RUNX3 Recombinant Rabbit Monoclonal Antibody (SD0803)
RUNX1/RUNX2/RUNX3 단백질을 인식하는 재조합 토끼 단클론 항체로 높은 특이성과 감도를 제공. Western blot, IHC, ICC/IF, Flow Cytometry에 적합. HEK293 발현 시스템 기반으로 로트 간 일관성 우수. 연구용으로만 사용 가능.
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Thermo Fisher Scientific RUNX1/RUNX2/RUNX3 Recombinant Rabbit Monoclonal Antibody (SD0803)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD0803 |
| Immunogen | Synthetic peptide within Human RUNX1 aa 404–453 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2809654 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
Target Information
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The encoded protein represents the alpha subunit of CBF and plays a role in normal hematopoiesis.
Chromosomal translocations involving this gene are associated with several types of leukemia.
Three transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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