Thermo Fisher Scientific RUNX1/RUNX2/RUNX3 Recombinant Rabbit Monoclonal Antibody (SD0803)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

Flow Cytometry (Flow)

1:50-1:100

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

SD0803

Immunogen

Synthetic peptide within Human RUNX1 aa 404-453 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RUNX1/RUNX2/RUNX3,uniProtId:Q01196-1,ncbiNodeId:9606,antigenRange:404-453,antigenLength:453,antigenImageFileName:MA5-32373_RUNX1RUNX2RUNX3_Q01196-1_Rabbit.svg,antigenImageFileNamePDP:MA5-32373_RUNX1RUNX2RUNX3_Q01196-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:RUNX1/RUNX2/RUNX3,uniProtId:Q13950-1,ncbiNodeId:9606,antigenRange:404-453,antigenLength:521,antigenImageFileName:MA5-32373_RUNX1RUNX2RUNX3_Q13950-1_Rabbit.svg,antigenImageFileNamePDP:MA5-32373_RUNX1RUNX2RUNX3_Q13950-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2809654

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Target Information

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are welldocumented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.