Thermo Fisher Scientific LL37 Polyclonal Antibody
LL37 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Reptile 시료 반응성 검증. WB, IHC 등 다양한 응용 가능. 항균 펩타이드 Cathelicidin 특이적. 연구용으로만 사용.
- 카탈로그번호
- OSC00130W-100UL
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:2,000
Miscellaneous PubMed (Misc)
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Reptile |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from Bungarus fasciatus Cathelicidin antimicrobial peptide (CAP-18, antibacterial protein LL-37, CAMP, CRAMP) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Cathelicidin antimicrobial peptide.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils.
Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells.
These molecules are essential for defense against invasive bacterial infection in skin.
Beyond direct antimicrobial function, Cathelicidins mediate innate and adaptive immunity, including endotoxin neutralization, angiogenesis, wound healing, neutrophil chemotaxis, and mast cell recruitment.
Cathelicidin antimicrobial peptides are considered prototypes for innovative drugs to treat infection and/or modulate immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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