Thermo Fisher Scientific Phospho-C/EBP alpha (Ser21) Polyclonal Antibody
C/EBP alpha 단백질의 Ser21 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도 정제 및 안정적 PBS/glycerol buffer로 제공. 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-C/EBP alpha (Ser21) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CEBPA (Accession P49715), corresponding to amino acid residues around phosphorylated Ser21 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816388 |
Product Specific Information
This antibody detects endogenous levels of C/EBP alpha only when phosphorylated at Serine 21.
Target Information
The C/EBP (CCAAT/enhancer binding protein) family of transcription factors—alpha, beta, delta, and epsilon—are widely expressed proteins found in various tissues. These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) that conforms to the consensus sequence (I/V/L)KXEP.
C/EBP transcription factors play major roles in metabolic regulation in liver and fat cells and are involved in adipocyte development.
Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation sites and display distinct functions in gene regulation.
C/EBPs also contribute to neurological processes such as nerve growth factor mediation, synaptic plasticity, and inflammatory response modulation in Alzheimer’s disease.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-104915_CEBP_alpha_P49715-1_Rabbit.svg, PA5-104915_CEBP_alpha_P49715-1_Rabbit_PDP.jpeg)
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