Thermo Fisher Scientific Phospho-VASP (Ser157) Polyclonal Antibody
Phospho-VASP (Ser157) 폴리클로날 항체로 사람, 생쥐, 랫트 시료에서 인산화된 VASP 검출에 적합. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도 정제 및 안정적 PBS/glycerol 버퍼로 장기 보관 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-VASP (Ser157) Polyclonal Antibody
Thermo Fisher Scientific Phospho-VASP (Ser157) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human VASP (Accession P50552), corresponding to amino acid residues around phosphorylated Ser157 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816391 |
Product Specific Information
This antibody detects endogenous levels of VASP only when phosphorylated at Serine 157.
Target Information
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. These proteins contain an EVH1 N-terminal domain that binds proteins with E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. The mid-region has a proline-rich domain that interacts with SH3 and WW domain-containing proteins, while the C-terminal EVH2 domain mediates tetramerization and binds G and F actin. VASP is associated with filamentous actin formation and plays a role in cell adhesion and motility, as well as intracellular signaling regulating integrin-extracellular matrix interactions. It is regulated by cyclic nucleotide-dependent kinases PKA and PKG.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.