Thermo Fisher Scientific ATF7 Polyclonal Antibody
ATF7 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ICC/IF 등에 사용 가능. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 40–90 of Human ATF7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718953 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
ATF7 plays important roles in early cell signaling. It binds the cAMP response element (CRE) sequence present in many viral and cellular promoters, and acts as an activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Although ATF7 has no intrinsic transcriptional activity, it activates transcription upon forming heterodimers with JUN or FOS. It can also bind TRE promoter sequences when heterodimerized with JUN family members. Isoforms 4 and 5 act as repressors or negative regulators of transcriptional activity, potentially by sequestering Thr-53 phosphorylating kinase in the cytoplasm, preventing activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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