Thermo Fisher Scientific APOE Monoclonal Antibody (4E4)
Apolipoprotein E4 특이적 단클론 항체로, ApoE2 및 ApoE3와 교차 반응 없음. Western blot, ELISA, IP, Dot blot 등 다양한 분석에 사용 가능. Human 시료 반응, Mouse IgG1 형식, Protein G 정제, 액상 형태로 제공. 연구용 전용 제품.
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Thermo Fisher Scientific APOE Monoclonal Antibody (4E4)
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:64,000 | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
| Dot blot (DB) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4E4 |
| Immunogen | Synthetic peptide corresponding to Human Apolipoprotein E4 conjugated to Keyhole Limpet Haemocyanin (KLH). Immunogen sequence: ApoE4 peptide. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539451 |
Product Specific Information
This antibody is specific for Apolipoprotein E4 and shows no cross-reactivity with ApoE2 or ApoE3.
Target Information
Apo E (Apolipoprotein E) plays an important role in lipid metabolism in plasma and is a constituent of various plasma lipoprotein-lipid particles. It is synthesized in the liver, brain, spleen, and kidney, and found at high concentrations in interstitial fluids. Apo E facilitates cholesterol transport from cells with excess cholesterol to cells requiring it and contributes to the formation of very low-density lipoproteins and chylomicrons. The Apo E gene is located on chromosome 19 at position 19q13.2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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