Thermo Fisher Scientific CLCN7 Polyclonal Antibody
Rabbit polyclonal antibody against CLCN7 for Western blot applications. Recognizes residues 783–796 of rat CLC-7. Supplied lyophilized, reconstitute with 50 µL deionized water. Store at -20°C. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)KDLARYRLGKGGLE, corresponding to amino acid residues 783–796 of rat CLC-7 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735665 |
Product Specific Information
- Product is shipped at room temperature as a lyophilized powder.
- Store at -20°C upon receipt.
- Reconstitution: add 50 µL of deionized water.
Target Information
The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7.
Defects in this gene are associated with osteopetrosis autosomal recessive type 4 (OPTB4, infantile malignant osteopetrosis type 2) and autosomal dominant osteopetrosis type 2 (OPTA2, Albers-Schonberg disease). Osteopetrosis is a rare genetic disease characterized by abnormally dense bone due to defective bone resorption. OPTA2 is the most common form, typically manifesting in adolescence or adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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