Thermo Fisher Scientific SPARC/Osteonectin Monoclonal Antibody (OSTN/3758)
인간 SPARC 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 Immunohistochemistry 등 다양한 분석에 사용 가능. 단백질 정제는 Protein A/G 방식이며, 보존제가 없는 PBS 용액 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SPARC/Osteonectin Monoclonal Antibody (OSTN/3758)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OSTN/3758 |
| Immunogen | Recombinant fragment (around aa1–200) of human SPARC protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SPARC gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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