Thermo Fisher Scientific JPH4 Polyclonal Antibody
JPH4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. PBS 용액 내 0.02% sodium azide 포함, 냉장 또는 장기 보관 시 -20°C에서 안정적입니다.
- 카탈로그번호
- PA520646
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific JPH4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the center of human JPH4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157001 |
Product Specific Information
- Suggested positive control: Mouse brain tissue lysate
- PA5-20646 can be used with blocking peptide PEP-0766
Target Information
Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are characteristic of excitable cells and mediate communication between cell surface and intracellular ion channels. Junctophilins (JPs) are essential components of these complexes, consisting of a hydrophobic C-terminal segment spanning the ER/SR membrane and a cytoplasmic domain with specific affinity for the PM.
Four JP subtypes have been identified:
- JPH1: Expressed in skeletal muscle
- JPH2: Found in all muscle cell types
- JPH3 and JPH4: Predominantly expressed in brain tissue
In the CNS, JPH3 and JPH4 contribute to subsurface cistern formation in neurons. Mice lacking both subtypes exhibit impaired learning, memory deficits, and abnormal nervous functions.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.