Thermo Fisher Scientific HAX1a Polyclonal Antibody
HAX1a 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 최적화되었습니다. 인간, 마우스, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1–2 µg/mL
A suggested positive control is human brain tissue lysate.
PA5-20649 can be used with blocking peptide PEP-0769.
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the amino terminus of human Hax1a |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153432 |
Target Information
The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay based on its ability to bind to the hematopoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including BH1- and BH2-like domains. It has been shown to interact with HIV viral protein R (Vpr), which is linked to T-cell apoptosis through activation of caspases 3 and 9. Hax1-mediated processing of HtrA2 (Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons under cytokine-limiting conditions.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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