Thermo Fisher Scientific PDGFRA Monoclonal Antibody (OTI1C10), TrueMAB
PDGFRA 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot과 IHC(P) 분석에 적합합니다. 사람 시료 반응성이 있으며, Lyophilized 형태로 제공됩니다. 연구용으로만 사용되며 고순도 친화 크로마토그래피 정제 제품입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 789–1089 of human PDGFRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PDGFRA is a cell surface receptor tyrosine kinase that binds platelet-derived growth factor family members. These growth factors act as mitogens for mesenchymal-origin cells. The receptor’s dimer composition (homodimer or heterodimer) depends on the bound growth factor. Knockout mouse studies show that PDGFRA is critical for kidney development, as heterozygous mice exhibit defective kidney phenotypes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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