Thermo Fisher Scientific beta Galactosidase Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Store vial at 4°C prior to restoration. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.

Beta-Galactosidase Antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process including delipidation, salt fractionation, and ion exchange chromatography, followed by extensive dialysis against the specified buffer.
Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum as well as purified and partially purified Beta Galactosidase (E. coli).
Cross-reactivity against Beta Galactosidase from other tissues and species may occur but has not been specifically determined. Very low background staining has been reported in various assays.

Target Information

Beta Galactosidase encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme.
This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates.
Mutations in this gene have been associated with GM1-gangliosidosis and Morquio B syndrome.
Diseases associated with GLB1 include GM1-Gangliosidosis Type I and Type II.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.