Thermo Fisher Scientific IL10RA Monoclonal Antibody (OTI1D10), TrueMAB
IL10RA 단백질을 인식하는 마우스 단클론 항체로, Western blot과 IHC(P)에서 검증됨. HEK293T 세포에서 발현된 인간 IL10RA 단백질로 면역화됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D10 |
| Immunogen | Full length human recombinant protein of human IL10RA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The IL10RA gene encodes a receptor for interleukin 10, structurally related to interferon receptors. It mediates the immunosuppressive signal of IL-10, inhibiting synthesis of proinflammatory cytokines. The receptor supports survival of progenitor myeloid cells via the IRS-2/PI3K/AKT pathway and activates JAK1 and TYK2 kinases upon stimulation. Two transcript variants exist, one protein-coding and one non-coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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