Thermo Fisher Scientific IL10RA Monoclonal Antibody (OTI1C7), TrueMAB
인간 IL10RA 단백질을 타겟으로 하는 Mouse IgG1 단클론 항체. Western blot에 최적화되어 있으며, 동결건조 형태로 제공. 연구용으로만 사용 가능하며, 높은 순도의 친화성 크로마토그래피 정제 제품.
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Applications
- Western Blot (WB)
Tested Dilution: 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C7 |
| Immunogen | Full length human recombinant protein of human IL10RA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The IL10RA gene encodes a receptor for interleukin 10, structurally related to interferon receptors. It mediates the immunosuppressive signal of IL-10, inhibiting synthesis of proinflammatory cytokines. This receptor promotes survival of progenitor myeloid cells via the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and one non-coding, are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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