Thermo Fisher Scientific SSEA1 Monoclonal Antibody (MEM-158), Biotin
SSEA1 (CD15) 항원을 인식하는 Biotin 결합 단클론 항체로, 인간 시료에 반응합니다. Flow Cytometry 및 Immunoprecipitation에 사용 가능합니다. 4°C에서 보관하며, 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 1–4 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-158 |
| Immunogen | Human granulocytes |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | TBS, pH 8 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071314 |
Additional Formats
Product Specific Information
This antibody reacts with CD15, a cell membrane molecule 3‑fucosyl‑N‑acetyllactosamine (3‑FAL) strongly expressed on the surface of granulocytes, monocytes, macrophages, and mast cells. It is also present on Langerhans cells and some myeloid precursor cells.
Target Information
CD15 (Lewis X, Le(x); stage specific embryonic antigen‑1, SSEA‑1) is a trisaccharide determinant (3‑fucosyl‑N‑acetyllactosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of various cell types such as granulocytes, mast cells, monocytes, macrophages, gastric mucosa cells, nervous system cells, and various tumour cells.
There are several variants of Lewis X, such as sialyl‑Lewis X or sulphated Lewis X.
Cells with high surface expression of Le(x) antigen exhibit strong self‑aggregation based on calcium‑dependent Le(x)‑Le(x) interaction, which is involved in embryo compaction and autoaggregation of teratocarcinoma cells.
Sialyl‑Le(x) and its isomer sialyl‑Le(a) are ligands of selectins.
CD15 expression has been extensively used to confirm diagnosis of Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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