Thermo Fisher Scientific Parkin Polyclonal Antibody
Parkin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC(P), ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체로 인간 시료 반응성. Alzheimer’s 뇌 조직을 양성 대조로 권장.
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:30 | - |
| Immunocytochemistry (ICC/IF) | 10 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from N-terminus of human parkin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.034 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.6, with 1% BSA |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2160083 |
Product Specific Information
Heat-mediated antigen retrieval is recommended prior to staining using a 10 mM citrate buffer (pH 6.0) for 10 minutes, followed by cooling at room temperature for 20 minutes.
After antigen retrieval, incubate samples with primary antibody for 30 minutes at room temperature.
A suggested positive control is Alzheimer’s brain tissue.
Target Information
The precise function of the Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation.
Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease.
Alternative splicing produces multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but currently lack transcript support.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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