Thermo Fisher Scientific PIM1 Recombinant Rabbit Monoclonal Antibody (ARC0175)
PIM1 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot, IHC, ELISA 등에 적합합니다. HEK293 세포에서 발현되었으며, 높은 특이성과 재현성을 제공합니다. 인간, 생쥐, 랫트 시료에 반응하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: –
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0175 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human PIM1 (P11309) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849248 |
Product Specific Information
Immunogen sequence:
MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG SVYSGIRVSD NLPVAIKHVE KDRISDWGEL PNGTRVPMEV VLLKKVSSGF
Target Information
The proto-oncogene PIM1 is upregulated in prostate cancer. PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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