Thermo Fisher Scientific N6-Methyladenosine (m6A) Recombinant Rabbit Monoclonal Antibody (6S5W2)
N6-Methyladenosine(m6A)를 표적하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체. ICC/IF, ELISA, Dot blot, RIP 등 다양한 응용 가능. 높은 특이성과 재현성을 제공하며, RNA 후전사적 변형 연구에 적합.
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Thermo Fisher Scientific N6-Methyladenosine (m6A) Recombinant Rabbit Monoclonal Antibody (6S5W2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Dot blot (DB) | 1:500–1:2,000 |
| RNA Immunoprecipitation (RIP) | 1:50–1:200 |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6S5W2 |
| Immunogen | Chemical compounds corresponding to N6-methyladenosine (m6A) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.05 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2849251 |
Target Information
N6-methyladenosine (m6A), or methylation of the N6 position of adenosine, is a posttranscriptional modification of RNA. Although historically poorly understood due to limited analytical methods, recent evidence indicates that it is one of the most common base modifications and serves as an important physiological regulator.
N6-methyladenosine levels increase significantly during brain development and are enriched near stop codons, microRNA-binding sites, and UTRs, suggesting a fundamental role in gene expression regulation. This modification is highly conserved between human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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