Thermo Fisher Scientific SULT1A1 Monoclonal Antibody (3C5H6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1:1,000-1:2,000

-

Immunoprecipitation (IP)

1-4 µL/mg of lysate

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3C5H6

Immunogen

Recombinant Human SULT1A1 protein (Glu2-Leu295) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SULT1A1,uniProtId:P50225-1,ncbiNodeId:9606,antigenRange:2-295,antigenLength:295,antigenImageFileName:MA5-29589_SULT1A1_P50225-1_House_mouse.svg,antigenImageFileNamePDP:MA5-29589_SULT1A1_P50225-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2785430

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human SULT1A1.

Target Information

The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily (namely SULT1, SULT2 and SULT3) show selectivity to certain substrate compounds. SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family. Functioning as a homodimer that is expressed in brain, liver, skin and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters and, via this catalytic activity, plays a role in the elimination of a variety of compounds from the body. Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.