Thermo Fisher Scientific STUB1 Recombinant Rabbit Monoclonal Antibody (006)
인체 STUB1 단백질을 인식하는 재조합 토끼 단클론 항체로 높은 특이성과 민감도를 제공. 보존제가 없는 액상 형태이며 IHC(P) 실험에 적합. 로트 간 일관성 및 동물 유래 성분이 없는 포뮬레이션.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 006 |
| Immunogen | Recombinant Human STUB1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785427 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits, followed by screening of individual clones to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
This antibody has specificity for Human STUB1.
Target Information
The carboxyl terminus of hsc70-interacting protein (CHIP) interacts with both hsc70 and hsp70. This 35 kDa cytoplasmic protein is highly expressed in striated muscle and across various cultured tissues. CHIP binds to the carboxyl terminus of hsc70 and hsp70, reducing ATPase activity and chaperone efficiency. It functions as an E3 ubiquitin-ligase within the ubiquitin-proteasome system, containing a U-box domain and acting in conjunction with hsc70 and hsp90.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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