Thermo Fisher Scientific IL6 Monoclonal Antibody (OTI3H6), TrueMAB
인간 IL-6 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 ICC/IF에 사용 가능. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 권장. 염증 및 면역 관련 연구에 적합한 고품질 연구용 항체.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 29–212 of human IL-6 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to reach a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
IL-6 encodes a cytokine involved in inflammation and B-cell maturation. It acts as an endogenous pyrogen capable of inducing fever in autoimmune diseases or infections. IL-6 is primarily expressed at sites of acute and chronic inflammation and triggers inflammatory transcriptional responses via the interleukin 6 receptor, alpha.
This gene is implicated in various inflammation-associated diseases, including diabetes mellitus susceptibility and systemic juvenile rheumatoid arthritis. Elevated IL-6 levels have been observed in viral infections such as COVID-19.
Diseases associated with IL6 include Kaposi Sarcoma and Systemic Juvenile Rheumatoid Arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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