
Thermo Fisher Scientific Phospho-MAP2K4 (Ser257) Recombinant Rabbit Monoclonal Antibody (SEK1MKK4S257-C5), FITC
Phospho-MAP2K4 (Ser257) 인산화 단백질을 특이적으로 인식하는 FITC 결합 재조합 토끼 단클론 항체. Flow Cytometry에 적합하며, Human, Mouse, Rat 등 다양한 종에 반응. Protein A/G 정제, PBS+BSA 완충액에 보관. 연구용 전용.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SEK1MKK4S257-C5 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C, store in dark |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897319 |
Additional Formats
- Unconjugated: MA5-37137
- APC: MA5-37140
- PE: MA5-37138
- Custom conjugation available upon request
Target Information
MAP2K4 (MEK4) is a serine/threonine kinase belonging to the STE7 family. It phosphorylates and activates JNK1, JNK2, and p38 kinases, preferentially targeting the tyrosine residue of JNKs.
MAP2K4 mediates cellular responses to stress and inflammatory cytokines and is implicated in carcinogenesis. Loss-of-function mutations have been found in lung and pancreatic tumors, while pro-oncogenic roles have also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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