Thermo Fisher Scientific Phospho-MAP2K4 (Ser257) Recombinant Rabbit Monoclonal Antibody (SEK1MKK4S257-C5)
Phospho-MAP2K4 (Ser257) 특이성을 가진 재조합 토끼 단일클론 항체로, Western blot 및 Flow cytometry에 적합합니다. Human, Mouse, Non-human primate 반응성이 있으며, HEK293 세포에서 발현된 IgG 형태입니다. 안정적 액상 제형으로 연구용에 최적화되어 있습니다.
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SEK1MKK4S257-C5 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.10% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897317 |
Additional Formats
Target Information
MAP2K4 (MEK4) is a serine/threonine kinase of the STE7 family that phosphorylates and activates JNK1 and JNK2 as well as p38. It preferentially phosphorylates the tyrosine residue of JNKs and mediates various physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines. MAP2K4 plays an important role in carcinogenesis; loss-of-function mutations have been found in lung and pancreatic tumors, while pro-oncogenic roles have also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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