Thermo Fisher Scientific Phospho-QRFP Receptor (Ser377) Polyclonal Antibody
Phospho-QRFP Receptor (Ser377) 특이적 폴리클로날 항체로 Western blot에 적합. Rabbit IgG 기반의 비결합형 항체이며, 항원 친화 크로마토그래피로 정제됨. 인간 QRFPR Ser377 인산화 부위 유래 합성 펩타이드 면역원 사용. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human QRFPR around the phosphorylation site Ser377. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
G protein-coupled receptors (GPRs) are a family of transmembrane receptors that transmit extracellular signals (ligand binding) into intracellular signals (G protein activation). GPR signaling is an evolutionarily conserved mechanism used by eukaryotes to sense environmental stimuli and mediate cell communication.
All GPRs have seven membrane-spanning domains, and their extracellular regions can be glycosylated. These loops contain conserved cysteine residues forming disulfide bonds that stabilize the receptor structure.
GPR103 is a 455 amino acid protein highly expressed in the brain, retina, trigeminal ganglion, hypothalamus, and vestibular nucleus. In peripheral tissues, it is expressed in the heart, kidney, and testis, and may regulate adrenal function. The hypothalamic neuropeptide 26RFa acts as an endogenous ligand for GPR103.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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