Thermo Fisher Scientific C9orf72 Monoclonal Antibody (GT1553)
C9orf72 단백질을 인식하는 Mouse IgG2a 모노클로날 항체로 WB, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 반응성. Recombinant N-terminus 항원을 이용해 제작, Protein A로 정제된 액상 형태. 신경퇴행성 질환 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT1553 |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human C9orf72. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2937982 |
Product Specific Information
- Store as concentrated solution.
- Centrifuge briefly prior to opening vial.
- Positive control: C9orf72-transfected 293T, Neuro2A, NIH-3T3, Raw264.7, C2C12, mouse brain, U87-MG, SK-N-SH, IMR32, SK-N-AS, 293T.
Target Information
C9orf72 may play a role in endosomal trafficking and autophagy. It interacts with HNRNPA1, HNRNPA2B1, UBQLN2, and small Rab GTPases.
C9orf72 localizes in the nucleus, cytoplasm, endosome, lysosome, and autophagosome.
Mutations in this gene can result in frontotemporal dementia and/or amyotrophic lateral sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: MA5-46910_C9orf72_Q96LT7-1_House_mouse.svg)
(이미지: MA5-46910_C9orf72_Q96LT7-1_House_mouse_PDP.jpeg)
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