Thermo Fisher Scientific IL-9 Polyclonal Antibody, HRP

Applications

Product Specifications

Product Specific Information

• Store vial at 4°C prior to restoration.
• For extended storage, aliquot contents and freeze at -20°C or below.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.
• This purified antibody has been heated to 56°C for 30 minutes.
• Recognizes both native and recombinant human IL-9 in cell supernatants and certain body fluids.
• A control of similarly diluted normal rabbit IgG is recommended.

Target Information

Interleukin 9 (IL-9) is produced by activated T helper 2 (Th2) lymphocytes.
IL-9 regulates cell types involved in classical Th2-associated asthma responses, including B and T lymphocytes, mast cells, eosinophils, and epithelial cells.
The mouse IL-9 cDNA encodes a 144 amino acid precursor protein with an 18 amino acid signal peptide that is cleaved to form the mature cysteine-rich protein (~14 kDa).
Native mouse IL-9 is heavily glycosylated.
TGF beta plays an important role in the differentiation of IL-17-producing T helper cells and inducible regulatory T cells by reprogramming Th2 cells to secrete IL-9, driving Th9 cell differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.