Thermo Fisher Scientific IL-2 Polyclonal Antibody, HRP

Thermo Fisher Scientific IL-2 Polyclonal Antibody, HRP

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Store vial at 4°C prior to restoration.
• For extended storage, aliquot contents and freeze at -20°C or below.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.
• This purified antibody has been heated to 56°C for 30 minutes.
• Recognizes both native and recombinant human IL-2 in cell supernatants and certain body fluids.
• A control of similarly diluted normal rabbit IgG is recommended.

Target Information

Interleukin 2 (IL-2) is an immuno-modulatory cytokine crucial for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is shared by IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, indicating precise gene regulation.
Disruption of IL-2-like genes in mice leads to ulcerative colitis-like disease, highlighting its essential role in immune response.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.