
Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI3G7), TrueMAB
LIPG 단백질을 인식하는 Mouse IgG2a 단클론 항체로, WB, IHC(P), IP에 사용 가능. 인간 시료 반응성. 동결건조 형태로 제공되며, PBS(8% 트레할로스) 완충액에 보관. 연구용으로 HDL 대사 및 지질 효소 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G7 |
| Immunogen | Full length human recombinant protein of human LIPG produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions locally to modulate lipoprotein metabolism. Overexpression of LIPG reduces HDL cholesterol levels, while deficiency increases HDL levels in animal models.
LIPG exhibits phospholipase activity, contributing to lipid metabolism and vascular biology. It belongs to the TG lipase family and acts as a carboxyl esterase that hydrolyzes high-density lipoproteins, emulsifies triglycerides, and binds to heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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