Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI5F2), TrueMAB
Human PTPRE 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. Lyophilized 형태로 제공되며, PBS buffer에 trehalose 포함. 세포 신호전달 및 성장 조절 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F2 |
| Immunogen | Full length human recombinant protein of human PTPRE produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The protein encoded by the PTPRE gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates cellular processes such as growth, differentiation, mitotic cycle, and oncogenic transformation.
Two alternatively spliced transcript variants exist:
- A receptor-type PTP with a short extracellular domain, single transmembrane region, and two tandem catalytic domains.
- A nonreceptor-type PTP with a distinct hydrophilic N-terminus.
Mouse studies suggest PTPRE plays regulatory roles in RAS-related signal transduction, cytokine-induced STAT signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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