Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI5E5), TrueMAB
Human PTPRE 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western Blot, IHC, ICC/IF에 사용 가능. Lyophilized 형태로 제공되며, PBS 및 trehalose buffer에 보관. 세포 신호전달 연구 및 단백질 발현 분석에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E5 |
| Immunogen | Full length human recombinant protein of human PTPRE produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The PTPRE gene encodes a member of the protein tyrosine phosphatase (PTP) family, which regulates cellular processes such as growth, differentiation, mitotic cycle, and oncogenic transformation.
Two alternatively spliced transcript variants exist:
- A receptor-type PTP with a short extracellular domain, single transmembrane region, and two tandem catalytic domains.
- A nonreceptor-type isoform containing a distinct hydrophilic N-terminus.
Mouse studies suggest PTPRE plays regulatory roles in RAS-related signal transduction, cytokine-induced STAT signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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