Thermo Fisher Scientific Transthyretin Recombinant Rabbit Monoclonal Antibody (JF1016)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select the best candidates for production.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

Target Information

Transthyretin (TTR), also known as prealbumin, is a plasma protein that functions as a transporter of thyroxine and retinal-binding protein. It is primarily produced in the liver and secreted into the plasma. TTR constitutes approximately 25% of cerebrospinal fluid (CSF) protein, suggesting selective transport across the blood-CSF barrier or synthesis within the central nervous system.
TTR is a component of neuritic plaques, neurofibrillary tangles, and microangiopathic lesions associated with senile cerebral amyloid. Over 40 different TTR gene mutations have been linked to amyloid deposition.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.