Thermo Fisher Scientific Phospho-SQSTM1 (Ser403) Polyclonal Antibody
인간, 생쥐, 랫트의 SQSTM1/p62 단백질 Ser403 인산화 형태를 특이적으로 검출하는 폴리클로날 항체. Western blot에 적합하며, 1 mg/mL 농도의 액상 형태로 제공. PBS와 글리세롤 버퍼에 보존되어 안정적. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-SQSTM1 (Ser403) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SQSTM1 (Accession Q13501), corresponding to amino acid residues around phosphorylated Ser403 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815871 |
Product Specific Information
This antibody detects endogenous levels of SQSTM1/p62 only when phosphorylated at Ser403.
Target Information
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-κB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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