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Thermo Fisher Scientific LRP6 Polyclonal Antibody
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LRP6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며 항원 친화 크로마토그래피로 정제되었습니다. Wnt/β-catenin 신호전달 연구용으로 적합합니다.
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마지막 업데이트 2025. 08. 05. 오전 06:47
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Thermo Fisher Scientific PA5101047 LRP6 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
696,000원VAT 포함 765,600원
Thermo Fisher Scientific · Thermo Fisher Scientific LRP6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LRP6 (Accession O75581), corresponding to amino acid residues G1454–Y1504 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815876 |
Product Specific Information
This antibody detects endogenous levels of total LRP6.
Target Information
LRP6 is essential for the Wnt/β-catenin signaling pathway, acting as a coreceptor with Frizzled for Wnt. It serves as a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. Interaction with DKK1 inhibits LRP6-mediated Wnt/β-catenin signaling through LRP6 removal via Kremen protein-mediated endocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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