Thermo Fisher Scientific CD249 (BP-1) Monoclonal Antibody (6C3), PE, eBioscience
마우스 BP-1(CD249)을 인식하는 6C3 클론의 Rat IgG2a 단클론항체로, PE로 표지되어 있습니다. Flow Cytometry에 최적화되어 있으며 1 µg/test로 사용됩니다. 565/576 nm에서 여기/방출하며, 4°C 암소 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1 µg/test
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Recommended Isotype Control | Rat IgG2a kappa Isotype Control (eBR2a), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C3 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_466014 |
Additional Formats
Product Specific Information
Description:
The 6C3 monoclonal antibody reacts with mouse BP-1 (CD249), also known as Ly-51 and 6C3 antigen. BP-1 is a 140 kDa type II transmembrane protein expressed as a disulfide-linked homodimer. It functions as an aminopeptidase A (APA) enzyme and is found on bone marrow stromal cells, thymic cortical epithelial cells, and early-stage mouse pre-B cells. BP-1 expression on pre-B cells can be upregulated by IL-7.
Applications Reported:
Validated for flow cytometric analysis.
Applications Tested:
Tested by flow cytometric analysis of mouse bone marrow cells. Use ≤1 µg per test (100 µL final volume). Optimal antibody titration is recommended.
- Excitation: 488–561 nm
- Emission: 578 nm
- Laser: Blue, Green, Yellow-Green
- Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD249 plays a role in the catabolic pathway of the renin-angiotensin system and may regulate growth and differentiation of early B-lineage cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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