Thermo Fisher Scientific Dynamin 2 Recombinant Rabbit Monoclonal Antibody (JM61-38)
Dynamin 2 단백질을 검출하기 위한 재조합 토끼 단일클론 항체로, WB, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능. 높은 특이성과 민감도, 로트 간 일관성, 동물 유래 성분이 없는 포뮬레이션을 제공. 연구용으로만 사용.
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Thermo Fisher Scientific Dynamin 2 Recombinant Rabbit Monoclonal Antibody (JM61-38)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM61-38 |
| Immunogen | Synthetic peptide within Human Dynamin 2 (aa 748–797) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810006 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
Dynamins are a subfamily of GTP-binding proteins sharing sequence similarity in the N-terminal GTPase domain. They associate with microtubules and are involved in cellular processes such as endocytosis, cell motility, and membrane remodeling (e.g., osteoclast bone resorption).
Dynamins interact with actin-binding and cytoskeletal proteins and can self-assemble to enhance GTPase activity. Multiple alternatively spliced transcripts encoding different proteins have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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