Thermo Fisher Scientific TAF4 Monoclonal Antibody (20TA-1B12)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:4,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

20TA-1B12

Immunogen

Recombinant TAF4 protein. Epitope is localized between aa 815 and 836. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TAF4,uniProtId:O00268-1,ncbiNodeId:9606,antigenRange:815-836,antigenLength:1085,antigenImageFileName:MA3-075_TAF4_O00268-1_House_mouse.svg,antigenImageFileNamePDP:MA3-075_TAF4_O00268-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2637134

Product Specific Information

MA3-075 detects TATA-Binding Protein (TBP) Associated factor 4 from human and mouse samples.

MA3-075 has been successfully used in Western blot and immunofluorescence applications.

The MA3-075 immunogen is a recombinant TAF4 protein. Epitope is localized between aa 815 and 836.

Target Information

TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFkB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.