Thermo Fisher Scientific HAX1 Polyclonal Antibody
HAX1 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 실험에 적합하며, 인간·마우스·랫에서 반응. 1 mg/mL 농도의 액상 제품으로 -20°C에 보관.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HAX1 (Accession O00165), corresponding to amino acid residues G221–F271 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899979 |
Product Specific Information
Antibody detects endogenous levels of total HAX1.
Target Information
The protein encoded by this gene associates with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene (mutations associated with autosomal-dominant polycystic kidney disease) and with the F-actin-binding protein cortactin.
Initially thought to be localized in mitochondria, recent studies show localization in the cell body.
Mutations in this gene result in autosomal recessive severe congenital neutropenia (Kostmann disease).
Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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