Thermo Fisher Scientific HBEGF Polyclonal Antibody
Thermo Fisher Scientific의 HBEGF Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작된 rabbit IgG 항체로, 액상 형태이며 -20°C에서 보관합니다. 세포 성장 및 EGFR 관련 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HBEGF (Accession Q99075), corresponding to amino acid residues T75–K125 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899980 |
Product Specific Information
Antibody detects endogenous levels of total HB EGF.
Target Information
HBEGF is a growth factor that mediates its effects via EGFR, ERBB2, and ERBB4. It is required for normal cardiac valve formation and heart function. HBEGF promotes smooth muscle cell proliferation and may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts but not for endothelial cells. It binds EGFR with higher affinity than EGF and is a more potent mitogen for smooth muscle cells. It also acts as a diphtheria toxin receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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