Thermo Fisher Scientific Phospho-SMAD3 (Ser213) Polyclonal Antibody
SMAD3 단백질의 Ser213 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 검증됨. 인간에 반응하며, 단백질 A 및 항원 친화 크로마토그래피로 정제됨. PBS buffer에 0.09% sodium azide 포함, 4°C 또는 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | — |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S213 of human SMAD3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2193169 |
Product Specific Information
This antibody is predicted to react with chicken, mouse, porcine, and rat based on sequence homology.
Target Information
SMAD3 belongs to the SMAD family of proteins, which are homologous to the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma. SMAD proteins act as signal transducers and transcriptional modulators mediating multiple signaling pathways. SMAD3 functions as a transcriptional modulator activated by transforming growth factor-beta (TGF-β) and may play a role in the regulation of carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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