Thermo Fisher Scientific Phospho-TrkA (Tyr791) Polyclonal Antibody
Human TrkA 단백질의 Tyr791 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot 및 Dot blot에 사용 가능. Protein A 및 항원 친화 크로마토그래피로 정제됨. PBS buffer에 보관하며 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Dot Blot (DB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y791 of human TrkA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10984502 |
Target Information
NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system.
TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway.
The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes.
Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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