Thermo Fisher Scientific Phospho-c-Jun (Thr243) Polyclonal Antibody
Phospho-c-Jun (Thr243) 폴리클로날 항체로, Western Blot 및 Dot blot에 적합. 인간 단백질에 반응하며, c-Jun 인산화 연구에 활용 가능. Rabbit IgG 기반으로 Protein A 및 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
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- PA512733
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Dot blot (DB) | 1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Thr243 of human JUN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10984157 |
Product Specific Information
This antibody is predicted to react with bovine, chicken, mouse, porcine, and rat based on sequence homology.
Target Information
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
It promotes activity of NR5A1 when phosphorylated by HIPK3, leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
It is also involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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