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Thermo Fisher Scientific DNMT1 Monoclonal Antibody (11H8), APC
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DNMT1 단백질을 검출하기 위한 APC 결합 단일클론 항체. Western blot 및 면역세포염색에 적합. 인간 및 생쥐 DNMT1을 교차 반응. 651/660 nm 형광 특성. 연구용으로만 사용 가능.
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- pk
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Thermo Fisher Scientific MA545335 DNMT1 Monoclonal Antibody (11H8), APC 100 ug pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific DNMT1 Monoclonal Antibody (11H8), APC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 11H8 |
| Immunogen | Synthetic peptide corresponding to amino acids 637–650 of human DNMT1 |
| Conjugate | APC (Allophycocyanin) |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- 2 µg/mL of MA5-45335 was sufficient for detection of Dnmt1 in 10 µg of mouse ES cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately 180 kDa protein.
- Cross-reacts with mouse DNMT1.
Target Information
This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein was identified by interaction with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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