
Thermo Fisher Scientific DNMT1 Monoclonal Antibody (11H8), PerCP
DNMT1 단백질 검출용 PerCP 결합 단클론 항체로 Western blot 및 면역세포화학에 적합함. 인간 DNMT1 637–650 아미노산 서열 기반 면역원으로 제작. 마우스 DNMT1에도 교차 반응. 482/675 nm 형광 특성, 4°C 보관.
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Thermo Fisher Scientific DNMT1 Monoclonal Antibody (11H8), PerCP
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 11H8 |
| Immunogen | Synthetic peptide corresponding to amino acids 637–650 of human DNMT1 |
| Conjugate | PerCP |
| Excitation/Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- 2 µg/mL of MA5-45337 was sufficient for detection of Dnmt1 in 10 µg of mouse ES cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately 180 kDa.
- Cross-reacts with mouse DNMT1.
Target Information
This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein interacts with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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