Thermo Fisher Scientific TNFRSF14 Monoclonal Antibody (4C9)
TNFRSF14 (HVEM)에 특이적인 Mouse IgG1 단일클론 항체로, 인간 시료에 반응합니다. Western blot과 ELISA에 적합하며, 보존제가 없는 PBS 용액 형태입니다. 세포 면역 반응 연구 및 HSV 관련 수용체 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C9 |
| Immunogen | TNFRSF14 (AAH02794.1, 38 a.a. approximately 200 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ALPSCKEDEY PVGSECCPKC SPGYRVKEAC GELTGTVCEP CPPGTYIAHL NGLSKCLQCQ MCDPAMGLRA SRNCSRTENA VCGCSPGHFC IVQDGDHCAA CRAYATSSPG QRVQKGGTES QDTLCQNCPP GTFSPNGTLE ECQHQTKCSW LVTKAGAGTS SSH
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily and acts as a cellular mediator of herpes simplex virus (HSV) entry. HSV glycoprotein D (gD) binds TNFRSF14 as part of the viral entry mechanism. The cytoplasmic region interacts with TRAF family members, mediating immune response signal transduction. Activation in T cells promotes proliferation and cytokine production, contributing to inflammation and enhanced CTL-mediated tumor immunity. TNFRSF14 may serve as a potential target for regulating cellular immune responses. Multiple alternatively spliced transcript variants exist, though not all full-length forms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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