Thermo Fisher Scientific TNFRSF14 Monoclonal Antibody (3B2)
TNFRSF14 (HVEM) 단백질을 인식하는 Mouse IgG1 단일클론 항체로, 인간 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 면역반응 및 HSV 진입 연구에 활용됩니다. 액상 형태로 제공되며, PBS buffer에 보존제 없이 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B2 |
| Immunogen | TNFRSF14 (AAH02794.1, 38 a.a. approximately 200 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ALPSCKEDEY PVGSECCPKC SPGYRVKEAC GELTGTVCEP CPPGTYIAHL NGLSKCLQCQ MCDPAMGLRA SRNCSRTENA VCGCSPGHFC IVQDGDHCAA CRAYATSSPG QRVQKGGTES QDTLCQNCPP GTFSPNGTLE ECQHQTKCSW LVTKAGAGTS SSH
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily and acts as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV glycoprotein D (gD) to TNFRSF14 facilitates viral entry. The cytoplasmic region interacts with TRAF family members to mediate immune signal transduction. Activation of TNFRSF14 in T cells enhances proliferation and cytokine production, contributing to inflammation and tumor immunity. Multiple alternatively spliced transcript variants exist, though not all are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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