Thermo Fisher Scientific NFE2L2 Polyclonal Antibody
NFE2L2(Nrf2) 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC 등 다양한 응용에 적합하며, 고순도 친화 크로마토그래피 정제. 인간, 생쥐, 랫트 반응성. -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NFE2L2 (Accession Q16236), corresponding to amino acid residues Q14–K64 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900307 |
Product Specific Information
Antibody detects endogenous levels of total Nrf2.
Target Information
Nfr1 (also designated TCF11), Nrf2, and Nfr3 are bZIP transcription factors that heterodimerize with Maf proteins to bind MARE (Maf recognition elements) sequences.
Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from the repressor protein Keap1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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