Thermo Fisher Scientific NOR-1 Polyclonal Antibody
NR4A3(NOR-1) 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합합니다. 인간, 마우스, 랫트, 비인간 영장류에 반응하며, 친화 크로마토그래피로 정제되었습니다. 액상 형태로 -20°C에 보관하며 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NR4A3 (Accession Q92570), corresponding to amino acid residues S390–L440. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900304 |
Product Specific Information
Antibody detects endogenous levels of total NR4A3.
Target Information
NOR-1 (NR4A3), a NR4 nerve growth factor-like receptor, plays roles in neuronal development, T-cell apoptosis, and cancer progression. It binds to NBRE (NGFI-B response element) to regulate the pro-opiomelanocortin (POMC) gene. NOR-1 is rapidly but transiently induced by various stimuli. Downregulation of NOR-1 and related NGFI-B family members correlates with addiction-prone behavior in Lewis rats. Three human isoforms are known: NOR-1, NOR-1β, and NOR-1 3′ variant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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