Thermo Fisher Scientific Cytokeratin 16 Monoclonal Antibody (LL025)
인간 Cytokeratin 16을 인식하는 Mouse IgG1 단일클론 항체 LL025. Western blot 및 IHC(Paraffin) 검증 완료. 단백질 A로 정제된 액상 형태로 제공되며, 0.5 mg/mL 농도. 연구용으로 세포막 및 세포질 위치 검출에 적합.
- 카탈로그번호
- 606-510
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LL025 |
| Immunogen | A synthetic peptide corresponding to the C-terminus of CK16 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Breast carcinoma
- Cellular location: Membrane and cytoplasm
Target Information
KRT16 is a member of the keratin gene family. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains and are clustered in chromosome region 17q12–q21.
This keratin is coexpressed with keratin 14 in epithelial tissues such as esophagus, tongue, and hair follicles.
Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma, and unilateral palmoplantar verrucous nevus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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